Figure 7

Alignment of PP2A sequence with the phosphatases of known 3-D structure. The first four entries correspond to phosphatases of known structure and the last entry correspond to PP2A which has been modelled. The last line in an alignment block corresponds to consensus secondary structure. This figure has been produced using JOY [60]. Key to JOY notation: Solvent inaccessible – UPPER CASE (O); Solvent accessible – lower case (o); Positive φ – italic (o); Cis peptide – breve (õ); Hydrogen bond to other sidechain – tilde (ö); Hydrgen bond to main chain amide – bold (o); Hydrogen bond to main chain carbonyl – underline (o); Disulphide bond – cedilla (ç).