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Figure 4 | BMC Structural Biology

Figure 4

From: Functional asymmetry in the lysyl-tRNA synthetase explored by molecular dynamics, free energy calculations and experiment

Figure 4

CD studies of LysU in a variety of ligand bound states. The continuous black line (A) shows the ellipticity of 2 μM LysU without ligands; the red dashed line (B) shows 2 μM LysU + 10 mM MgCl2; the green dashed-dotted line (C) shows 2 μM LysU + 10 mM MgCl2 + 1 mM lysine; the blue dotted line (D) shows 2 μM LysU + 10 mM MgCl2 + 1 mM lysine + 250 μM AMPPCP; the brown dash dot dot line shows 2 μM LysU + 10 mM MgCl2 + 250 μM AMPPCP(E).

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