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Figure 4 | BMC Structural Biology

Figure 4

From: An inactivated nuclease-like domain in RecC with novel function: implications for evolution

Figure 4

Comparison of modes of DNA binding to superimposed nuclease(-like) domains. The domain structures are those of a) PvuII (PDB code 1pvi; [22] b) vsr exonuclease (PDB code 1odg; [23]) and c) RecC (PDB code 1w36; [18]). Protein chains are coloured in a spectrum from blue (N-terminus) to red (C-terminus) while DNA is coloured uniformly pink. In order to illustrate the approximate locations of the catalytic sites, selected catalytic residues are shown for PvuII (D58 and E58) and vsr exonuclease (D51 and H69). DNA termini are labelled, as is the "hoop" in RecC.

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