Target (ST3Gal I) – template (CstII, PDB id 1RO7) sequence alignment generated by the fold-recognition servers. The alignments were generated by the indicated servers when ST3Gal I sequence from the L-motif region till the C-terminus was used as query. Regions of alignment that are same for the four servers are highlighted. The alignments for the region spanning residues 215 to 254 of ST3Gal I generated by the four servers are different. The mismatch in alignment of secondary structures of target -- template are also seen in these regions. The helices are highlighted as yellow and the strands are shown in blue (as in Figure 1). Such a disagreement for this region is seen in the case of other ST3Gals also.