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Figure 7 | BMC Structural Biology

Figure 7

From: Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for α-keto acid binding

Figure 7

View of the binding pockets and connecting channel. A: a long water channel (red mesh) located at the interface of the two monomers opens onto both pyruvate binding sites. B, C, D: Models showing how various ligands may fit into the binding pocket : oxobutyrate (B), oxovalerate (C) and 4-methyl-2 oxovalerate (D). The K d 's found for these molecules is indicated in Figure 1.

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BMC Structural Biology

ISSN: 1472-6807

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