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Figure 8 | BMC Structural Biology

Figure 8

From: Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for α-keto acid binding

Figure 8

Model of interaction of the TakP dimer with its membrane partners TakQ and TakM. In this model, a membrane-bound pathway is hypothesized (heavy arrows). The channel at the dimer interface would facilitates the passage of the substrate from the solvent-exposed monomer to the other monomer that interacts with a membrane subunit. This model does not exclude the possibility that binding of the loaded ESR may happen (light arrows).

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BMC Structural Biology

ISSN: 1472-6807

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