Figure 6

Stereo view of the ensemble of 20 lowest interaction energy structures of the R21A Spc-SH3:P41 complex. The structures (blue ribbons) are superimposed on the X-ray structure of the Abl-SH3:P41 complex (pdb 1BBZ, red) for comparison. Superposition was done on the backbone N,Ca,C' atoms of p41 and residues 8–17, 21–35, 39–45 and 50–59 of R21A Spc-SH3 to 2–11, 15–29, 34–40 and 45–54 of Abl-SH3, respectively.