Figure 1
From: Occurrence of protein structure elements in conserved sequence regions
A scheme of the analysis approach and a sample structure. (A) Counting secondary structure elements in conserved protein regions and estimating their occurrence in all of the protein. A sample protein is shown with three conserved regions in color (b), and the secondary structure assignment for one of the regions (c). Sampling of random regions with the same widths as the conserved regions is schematically shown in (a1-n). (B) Structure of MUG G:T/U mismatch-specific DNA glycosylase (PDB Id 1mug) in cartoon representation, with conserved regions colored by secondary structure (strand yellow, loop green, helix red, and turn orange). There are relatively more strands in conserved regions than helices: three out of four strands are in conserved regions, while four out of seven helices are in conserved regions.