Table 4 Number, mean HINT scores and mean Ranks of waters initially classified by role.

H _{protein-water}

H _DNA-water

H _TOTAL

R _{protein-water}

R _DNA-water

R _TOTAL

All H ₂ O interacting with DNA backbone

535

-36

426

390

1.9

1.3

3.2

All H ₂ O interacting with nucleotide base

461

32

324

356

1.7

1.6

3.3

All non-bridging H ₂ O

212

-17

281

264

1.6

1.2

2.8

All H ₂ O bridging nucleotide base and protein

249

71

361

432

1.9

1.8

3.7

H ₂ O bridging nucleotide base and protein's

side-chain

218

94

360

453

1.9

1.8

3.7

backbone

20

-120

400

280

1.6

1.9

3.5

backbone & side-chain

11

36

310

346

2.8

1.7

4.6