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Figure 1 | BMC Structural Biology

Figure 1

From: Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes

Figure 1

Chemical structures of the inhibitors used in this study. X-ray structures of E. coli MetAP complexed with 1–3 have been reported previously [17, 33], and those with 4–8 are reported here. They are potent inhibitors of the Mn(II)-form of E. coli MetAP with IC50 values of 0.51, 0.69, 0.29, 1.1, 0.56, 0.37, 1.6 and 1.2 μM, respectively [18].

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BMC Structural Biology

ISSN: 1472-6807

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