Figure 8
From: Solution structure of the Legionella pneumophila Mip-rapamycin complex
Topology of the binding pocket in different structures of Mip and FKBP12. a) Crystal structure of Mip (pdb code 1FD9 [6]); b) solution structure of Mip77–213 (pdb code 2UZ5); c) solution structure of the Mip77–213-rapamycin complex (pdb code 2VCD); d) crystal structure of the FKBP12-rapamycin complex (pdb code 1FKB [26]). Side chains forming the binding pocket are shown as sticks. The key residues Y-82 (FKBP12) and Y-185 (Mip) are highlighted in grey in each structure.