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Figure 5 | BMC Structural Biology

Figure 5

From: A multi-template combination algorithm for protein comparative modeling

Figure 5

An good example (CASP7 target T0315) of using multiple templates to improve model quality. (1) The superimposition of the experimental structure (PDB code: 2GZX) and the best template (PDB code: 1J6O). Blue and red lines represent the backbone of the experimental and template structures, respectively. One bad region is identified. (2) The superimposition of the experimental structure and a good template (PDB code: 1YIX). One bad region is identified. (3) The superimposition of the experimental structure and the model generated by 3Dpro during CASP7, based on multiple templates). Two bad regions in (1) and (2) are corrected in the model (3). Most other regions of the model are also closer to the experimental structure than the two templates.

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