Skip to main content

Advertisement

Table 3 Rotamers changes in the ecRBP (1URP molecule A/2DRI) and tmRBP (apoprotein molecule A/ribose-bound form) binding pocket residues.

From: Ligand-induced conformational changes in a thermophilic ribose-binding protein

  ecRBP tmRBP
  Δχ1 (°) Δχ2 (°) Δχ3 (°) Δχ4 (°) (Σ|Δχ|)/N χ (°) Δχ1 (°) Δχ2 (°) Δχ3 (°) Δχ4 (°) (Σ|Δχ|)/N χ (°)
ASN13 12 -13    13 13 -1    7
PHE15 -1 16    8 26 -173    100
PHE16 -7 10    8 -17 26    22
ASP89 -18 17    18 -1 19    10
ARG90 26 -17 -27 70 35 -1 -5 5 0 3
ARG141/148 -1 -12 -7 -6 6 0 -12 4 -19 9
PHE164/172 0 0    0 1 4    3
ASN190/198 -7 -4    5 4 -8    6
ASP215/223 14 4    9 -1 6    3
↑GLN235/244 -20 -7 45   24 -3 9 -29   14
  1. C-terminal amino acids are in bold face type; the hinge amino acid that interacts with ribose is indicated by an arrow. Where amino acid numbering differs, ecRBP residues are listed first.