Surface electrostatic potential of mthSBDS. Three different views, each 90° apart along the vertical axis of the figure, are shown with colors ranging from red (-0.5 V) to blue (0.5 V). Labels indicate domains I, II and III. The electrostatic potential was calculated using the PARSE forcefield at an implicit ionic strength of 150 mM NaCl and mapped on the solvent accessible surface of mthSBDS. The FYSH domain is at the bottom of the figure. On the right panel, the positions of selected positively charged residues are indicated with green arrows (see text for details).