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Figure 7 | BMC Structural Biology

Figure 7

From: An in silico study of the molecular basis of B-RAF activation and conformational stability

Figure 7

Some of the residues participating in indirect disordering of the HBN in B-RAFWT. A close look at the conformation of the major catalytic residues, the DFG motif and the P-loop residues participating in the disordering of the identified hydrogen bond network in the unbounded B-RAFWT after 15 ns of simulation time. The dotted lines and the adjacent values present the H-bonds and their distances.

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