Figure 10From: Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutationsHeavy atom root-mean-squared deviation (RMSD, in Ã…, relative to the initial structure) of JH1 domain (defined as residue 840 to 1129), JH2 domain (defined as residue 543 to 839), and of JH1/JH2 together (defined as residue 543 to 1129) for the wild-type JAK2.Back to article page