Figure 3

Trace residues for partition P08 mapped onto the Axin DIX domain. (A) The DIX domain is shown as grey ribbon representation and trace residues are shown as coloured balls: conserved and buried residues are in blue, class-specific and buried in red, conserved and surface exposed in green, class-specific and exposed in yellow. Non-trace residues are coloured grey. Residues annotated with red text have been reported in the literature (see Table 1). (B) The DIX domain shown as a ball model in grey, with residues whose substitution affect function shown in orange. (C) The Axin DIX domain rotated 90° relative to figures in (A).