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Table 3 EPPIC performance based on UniProt 2014_05

From: A PDB-wide, evolution-based assessment of protein-protein interfaces

DataSet N(>10 homo.) Method Sensitivity Specificity Accuracy MCC
DC   Geometry 0.8025 0.7284 0.7654 0.5323
Bio 81(73) Core Rim 0.8514 0.6462 0.7554 0.5111
Xtal 81(73) Core Surface 0.8649 0.7059 0.7887 0.5800
   Final 0.9012 0.7160 0.8086 0.6281
Ponstingl   Geometry 0.8721 0.9231 0.8913 0.7789
Bio 86(75) Core Rim 0.8784 0.7143 0.8333 0.5863
Xtal 52(46) Core Surface 0.8472 0.8571 0.8500 0.6631
   Final 0.9070 0.9038 0.9058 0.8025
Many   Geometry 0.7549 0.9451 0.8513 0.7143
Bio 2831(2508) Core Rim 0.8206 0.6580 0.7582 0.4839
Xtal 2913(2368) Core Surface 0.8900 0.8236 0.8641 0.7142
   Final 0.8531 0.9046 0.8792 0.7590