Fig. 1
From: Three-dimensional structure model and predicted ATP interaction rewiring of a deviant RNA ligase 2
Delineation of the Nucleotidyltransferase domain. Multiple alignment of RNA ligases 2 from Enterobacteriophage T4 (T4RNL2), Diplonema papillatum (DpRNL), Naegleria gruberi (NgRNL), and four kinetoplastids, Leishmania infantum JPCM5 (LiREL1, LiREL2), L. major Friedlin (LmREL1, LmREL2), Trypanosoma vivax Y486 (TvREL1, TvREL2), and T. brucei TREU927 (TbREL1, TbREL2). The six sub-domains (I, II, III, IIIA, IV and V) highlighted in orange, cyan, green, blue, yellow and red, respectively are clearly detectable in DpRNL