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Table 1 Identification of the ligase family to which belongs DpRNLa

From: Three-dimensional structure model and predicted ATP interaction rewiring of a deviant RNA ligase 2

Family

PFAM

D. papillatum DpRNL

N. gruberi XP_002674912.1

T. brucei KREL1

T. brucei KREL2

DNA ligase

 [N] ATP dependent

PF01068

3.30 × 10−5

2.60 × 10−5

1.00 × 10−3

1.60 × 10−6

 [N] NAD dependent

PF01653

2.20 × 10−2

2.90 × 10−2

–

4.70 × 10−1

RNA ligase

 [N] Rnl1 defense, splicing

PF09511

2.70 × 10−1

1.30 × 10−2

3.40 × 10−1

4.00 × 10−1

  [N] Rnl2 editing

PF09414

4.90 × 10−12

3.20 × 10−9

7.90 × 10−55

4.30 × 10−53

 [N] Capping

PF01331

2.70 × 10−1

1.70 × 10−1

9.10 × 10−3

2.10 × 10−1

 LigT

PF02834

–

–

–

–

 RtcB splicing

PF01139

–

–

4.80 × 10−1

–

  1. aFamily names preceded by an [N] are those containing a Nucleotidyltransferase domain. Each model was searched with HMMer against all the proteins of Diplonema papillatum, Naegleria gruberi and Trypanosoma brucei TREU927. This table presents the E-value for the RNA ligases 2 proteins only. The line for the PFAM domain specific for RNA ligases 2 is in bold