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Fig. 4 | BMC Structural Biology

Fig. 4

From: Investigation of allosteric coupling in human β2-adrenergic receptor in the presence of intracellular loop 3

Fig. 4

Simultaneous conformational changes in extracellular and intracellular parts of the receptor. a, b RMSD of intracellular part of TM6 with respect to active state (PDB id: 3P0G) vs. distance between Ser207-Oγ and Asp113-Cγ in two continuation runs (green dots) together with the original MD1μs run (red dots). c Extracellular view of the binding site and d side view of TM6 for which the active state, initial and final snapshots of MD1μs run were colored in green, blue and magenta, respectively

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