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Table 2 SOD1 mutant clustering by Hm rows

From: Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

No SOD1 mutants SH ST, years
1 A4V, V7E, G37R, G41S, G41D, H43R, H46R, H48Q, D76V, L84F, L84 V, G85R, N86 K, A89V, D90A, G93R, E100G, D101N, S105 L, L106 V, I112T, D124V, D125H, G127R, N139H, L144S 0.00 5.6 ± 5.4
2 G10 V, L38 V, I112M, V148I 0.31 ± 0.06 2.0 ± 0.7
3 F20C, G114A 0.94 ± 0.06 2.3 ± 0.4
4 C6G, L8Q, G12R 0.67 ± 0.06 2.4 ± 2.2
  1. ST denotes mean survival time of patients with mutations from the corresponding cluster. Standard deviations were given after “±” symbol