Fig. 5

Comparison between eIF1A and eIF1AD. a Center, structure alignment between the folded domains of human eIF1A (1d7q.pdb, blue) and eIF1AD (2dgy.pdb, gold). The eIF1A and eIF1AD structures are shown on the left and right, respectively. b Sequence alignment of the folded domains of eIF1A (top) and eIF1AD (bottom). Identical residues are red; similar residues are orange; and conserved hydrophobic residues are gold. Residue numbers and secondary structure elements for human eIF1A are shown above the alignment. Residue numbers and secondary structure elements for human eIF1AD are shown below the alignment