Fig. 1
From: Crystal structure of carbonic anhydrase CaNce103p from the pathogenic yeast Candida albicans
Multiple alignment of fungal β-CAs and secondary structure prediction of CaNce103p. Secondary structure prediction of CaNce103p and sequence multialignment of CaNce103p and CAs from Candida parapsilosis, (CpNce103p, CGDID: CAL0000147197), Saccharomyces cerevisiae (ScNce103, Swiss-Prot: P53615), Sordaria macrospora (CAS1, Swiss-Prot: C1L335), Cryptococcus neoformans (Can2, EMBL: Q314V7). The predicted secondary structure regions are indicated as follows: H-Helix, E-Sheet, T-Turn, C-Coil. Black and gray backgrounds denote identical and similar amino acid residues, respectively. Secondary structural elements (X-ray CaNce103p) found in ∆29_CaNce103p are shown as helices and arrows (strands). The black arrows indicate sites of truncation. All sequences were obtained from NCBI databases. Prediction of secondary structure and multialignment was performed using the programs CFSSP [16], MultAlin [28] and ESPript [29]