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Fig. 8 | BMC Structural Biology

Fig. 8

From: A new technique for predicting intrinsically disordered regions based on average distance map constructed with inter-residue average distance statistics

Fig. 8

a Dimer part of p53 tetramerization domain. Monomer of p53 exhibits one α-helix and one β-strand. b The sequences and comparisons of the results of prediction techniques for the monomer and the dimer. The positions of an α-helix and a β-strand are indicated by red and blue letters in sequences p53 (monomer) and p53 (dimer). A segment with a red double arrow means the position of IDR. A blue double arrow means a segment predicted as IDR by Biomine, PrDOS, DISOPRED, or the ADM technique in the present study. It is assumed that the monomer exhibits the IDP property and the dimer exhibits ordered structures [24]. A red rectangle in the PrDOS and ADM predictions denotes the parts which show the predicted ordered regions only in the dimer

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