Section edited by Jean-Luc Pellequer
This section incorporates all aspects of the structural analysis of biological macromolecules using techniques in microscopy including but not limited to: studies incorporating substantial analysis by electron microscopy, atomic force microscopy, tomography and/or chromatography as well as image processing tools.
P-glycoprotein (ABCB1) is an ATP-binding cassette transporter that plays an important role in the clearance of drugs and xenobiotics and is associated with multi-drug resistance in cancer. Although several P-g...
Synchrotron radiation facilities are pillars of modern structural biology. Small-Angle X-ray scattering performed at synchrotron sources is often used to characterize the shape of biological macromolecules. A ...
Picking images of particles in cryo-electron micrographs is an important step in solving the 3D structures of large macromolecular assemblies. However, in order to achieve sub-nanometre resolution it is often ...