Table 1 Plasomodium peroxiredoxin orthologues and corresponding PDB codes for solved structures
Subfamily | Name | Mechanistic Classification | Cellular Location | PlasmoDB ID | PDB ID | Reference |
|---|---|---|---|---|---|---|
Prx1 | Pf Trx-Px1 | 2-Cys (C50, C170) | cytosolic | PF14_0368 | Â | [15] |
| Â | Pv Trx-Px1 | 2-Cys (C50, C170) | cytosolic | PVX_118545 | (2H66, 2I81) | this work |
| Â | Py Trx-Px1 | 2-Cys (C50, C170) | cytosolic | PY00414 | (2H01) | this work |
| Â | Pb Trx-Px1 | 2-Cys (C50, C169) | cytosolic | PB000037.01.0 | Â | Â |
| Â | Pk Trx-Px1 | 2-Cys (C50, C170) | cytosolic | PKH_126740 | Â | Â |
| Â | Pf Trx-Px2 | 2-Cys (C67, C187) | mitochondrial | PFL0725w | (2C0D) | |
| Â | Pv Trx-Px2 | 2-Cys (C67, C187) | mitochondrial | PVX_123435 | Â | Â |
| Â | Py Trx-Px2 | 2-Cys (C67, C187) | mitochondrial | PY02747 | Â | Â |
| Â | Pb Trx-Px2 | 2-Cys (C59, C179) | mitochondrial | PB001545.02.0 | Â | Â |
| Â | Pk Trx-Px2 | 2-Cys (C67, C187) | mitochondrial | PKH_143220 | Â | Â |
Prx6 | Pf Trx-Px1 | 1-Cys (C47) | cytosolic | PF08_0131 | Â | Â |
| Â | Pv Trx-Px1 | 1-Cys (C47) | cytosolic | PVX_093630 | Â | Â |
| Â | Py Trx-Px1 | 1-Cys (C47) | cytosolic | PY04285 | (3TB2) | this work |
| Â | Pb Trx-Px1 | 1-Cys (C47) | cytosolic | PB000600.02.0 | Â | Â |
| Â | Pk Trx-Px1 | 1-Cys (C47) | cytosolic | PKH_011610 | Â | Â |
Prx5 | Pf Trx-Px1 | 1-Cys (C117) | apicoplast | MAL7P1.159 | (1XIY) | [17] |
| Â | Pv Trx-Px1 | 1-Cys (C114) | apicoplast | PVX_081760 | Â | Â |
| Â | Py Trx-Px1 | 1-Cys (C122) | apicoplast | PY01475 | Â | Â |
| Â | Pb Trx-Px1 | 1-Cys (C28) | apicoplast | PB000177.01.0 | Â | Â |
| Â | Pk Trx-Px1 | 1-Cys (C114) | apicoplast | PKH_021360 | Â | Â |
BCP | Pf nPrx | 1-Cys (C56) | nuclear | PF10_0268 | Â | |
| Â | Pv nPrx | 1-Cys (C52) | nuclear | PVX_111355 | Â | Â |
| Â | Py nPrx | 1-Cys (C52) | nuclear | PY03834 | Â | Â |
| Â | Pb nPrx | 1-Cys (C61) | nuclear | PBANKA_051140 | Â | Â |
| Â | Pk nPrx | 1-Cys (C52) | nuclear | PKH_061160 | Â | Â |