Figure 4

Performance of different metrics for selecting the best model for the globin protein family. The C_α RMSD selected by a particular metric is shown by a line connecting each member of the family. The different metrics are sequence identity, sequence similarity based on several different scoring matrices (the best results are shown, based on using the BLOSUM62 matrix), and the all-atom scoring function. The best model that could have been selected is shown by a solid line. On average, using the all-atom function improves model quality by 0.8 Å C_α RMSD compared to only using sequence identity to select the template structure. The best improvement that could have been achieved on average is 0.9 Å C_α RMSD.