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BMC Structural Biology

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  1. Content type: Research article

    Multimeric naphthoquinones are redox-active compounds that exhibit antineoplastic, antiprotozoal, and antiviral activities. Due to their multimodal effect on perturbation of cellular oxidative state, these com...

    Authors: Lakshmi Swarna Mukhi Pidugu, J.C. Emmanuel Mbimba, Muqeet Ahmad, Edwin Pozharski, Edward A. Sausville, Ashkan Emadi and Eric A. Toth

    Citation: BMC Structural Biology 2016 16:1

    Published on:

  2. Content type: Research article

    Hazara virus (HAZV) is a member of the Bunyaviridae family of segmented negative stranded RNA viruses, and shares the same serogroup as Crimean-Congo haemorrhagic fever virus (CCHFV). CCHFV is responsible for fat...

    Authors: Rebecca Surtees, Antonio Ariza, Emma K. Punch, Chi H. Trinh, Stuart D. Dowall, Roger Hewson, Julian A. Hiscox, John N. Barr and Thomas A. Edwards

    Citation: BMC Structural Biology 2015 15:24

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  3. Content type: Research article

    Protein-protein interactions (PPIs) mediate the vast majority of biological processes, therefore, significant efforts have been directed to investigate PPIs to fully comprehend cellular functions. Predicting c...

    Authors: Surabhi Maheshwari and Michal Brylinski

    Citation: BMC Structural Biology 2015 15:23

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  4. Content type: Research article

    Many β-strands are not flat but bend and/or twist. However, although almost all β-strands have a twist, not all have a bend, suggesting that the underlying force(s) driving β-strand bending is distinct from th...

    Authors: Kazuo Fujiwara, Shinichi Ebisawa, Yuka Watanabe, Hiromi Fujiwara and Masamichi Ikeguchi

    Citation: BMC Structural Biology 2015 15:21

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  5. Content type: Research article

    RNA ligases 2 are scarce and scattered across the tree of life. Two members of this family are well studied: the mitochondrial RNA editing ligase from the parasitic trypanosomes (Kinetoplastea), a promising dr...

    Authors: Sandrine Moreira, Emmanuel Noutahi, Guillaume Lamoureux and Gertraud Burger

    Citation: BMC Structural Biology 2015 15:20

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  6. Content type: Research article

    Stimulation of phospholipase Cβ (PLCβ) by the activated α-subunit of Gq (Gαq) constitutes a major signaling pathway for cellular regulation, and structural studies have recently revealed the molecular interaction...

    Authors: Dawna HT Kwan, Ka M. Wong, Anthony SL Chan, Lisa Y. Yung and Yung H. Wong

    Citation: BMC Structural Biology 2015 15:18

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  7. Content type: Research article

    The c-Jun N-terminal kinases (JNKs), members of the mitogen-activated protein kinase (MAPK) family, engage in diverse cellular responses to signals produced under normal development and stress conditions. In Dros...

    Authors: Sarin Chimnaronk, Jatuporn Sitthiroongruang, Kanokporn Srisucharitpanit, Monrudee Srisaisup, Albert J. Ketterman and Panadda Boonserm

    Citation: BMC Structural Biology 2015 15:17

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  8. Content type: Research article

    Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface. Upstream of the catalytic domain of NanA is a domain that conforms to the s...

    Authors: Lei Yang, Helen Connaris, Jane A. Potter and Garry L. Taylor

    Citation: BMC Structural Biology 2015 15:15

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    The Erratum to this article has been published in BMC Structural Biology 2015 15:19

  9. Content type: Research article

    Calicheamicins (CAL) are enedyine natural products with potent antibiotic and cytotoxic activity, used in anticancer therapy. The O-methyltransferase CalO6 is proposed to catalyze methylation of the hydroxyl moie...

    Authors: Oleg V. Tsodikov, Caixia Hou, Christopher T. Walsh and Sylvie Garneau-Tsodikova

    Citation: BMC Structural Biology 2015 15:13

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  10. Content type: Research article

    Stationary phase survival proteins (Sps) were found in Firmicutes as having analogous domain compositions, and in some cases genome context, as the resuscitation promoting factors of Actinobacteria, but with a...

    Authors: Doris H.X. Quay, Ambrose R. Cole, Adam Cryar, Konstantinos Thalassinos, Mark A. Williams, Sanjib Bhakta and Nicholas H. Keep

    Citation: BMC Structural Biology 2015 15:12

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  11. Content type: Research article

    Helicobacter pylori is an important factor in the development of diseases such as ulcer and gastric cancer. This bacterium uses a periplasmic transporter, UreI, to deliver urea to the ...

    Authors: Javier Cáceres-Delpiano, Jaime Teneb, Rodrigo Mansilla, Apolinaria García and Alexis Salas-Burgos

    Citation: BMC Structural Biology 2015 15:11

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  12. Content type: Research article

    Uracil-DNA glycosylases are evolutionarily conserved DNA repair enzymes. However, vaccinia virus uracil-DNA glycosylase (known as D4), also serves as an intrinsic and essential component of the processive DNA ...

    Authors: Norbert Schormann, Surajit Banerjee, Robert Ricciardi and Debasish Chattopadhyay

    Citation: BMC Structural Biology 2015 15:10

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  13. Content type: Research article

    The coronavirus 3 chymotrypsin-like protease (3CLpro) is a validated target in the design of potential anticoronavirus inhibitors. The high degree of homology within the protease’s active site and substrate conse...

    Authors: Michael Berry, Burtram Fielding and Junaid Gamieldien

    Citation: BMC Structural Biology 2015 15:8

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  14. Content type: Research article

    Type IV pili are widely expressed among Gram-negative bacteria, where they are involved in biofilm formation, serve in the transfer of DNA, motility and in the bacterial attachment to various surfaces. Type IV...

    Authors: Manuela Gorgel, Jakob Jensen Ulstrup, Andreas Bøggild, Nykola C Jones, Søren V Hoffmann, Poul Nissen and Thomas Boesen

    Citation: BMC Structural Biology 2015 15:4

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  15. Content type: Research article

    Deinococcus radiodurans is an extremely radiation and desiccation resistant bacterium which can tolerate radiation doses up to 5,000 Grays without losing viability. We are studying the role of ...

    Authors: Laila Niiranen, Kjersti Lian, Kenneth A Johnson and Elin Moe

    Citation: BMC Structural Biology 2015 15:5

    Published on:

  16. Content type: Research article

    Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. It is also secreted by the intracellular parasite Leishmania to modula...

    Authors: Plínio Salmazo Vieira, Priscila Oliveira de Giuseppe, Mario Tyago Murakami and Arthur Henrique Cavalcante de Oliveira

    Citation: BMC Structural Biology 2015 15:2

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2016 Journal Metrics

  • Citation Impact
    1.771 - 2-year Impact Factor
    1.696 - 5-year Impact Factor
    0.612 - Source Normalized Impact per Paper (SNIP)
    0.984 - SCImago Journal Rank (SJR)

    Usage 
    188,808 downloads
    1110 Usage Factor


    Social Media Impact
    22 mentions

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