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  1. Arabidopsis thaliana copper metallochaperone CCH is a functional homologue of yeast antioxidant ATX1, involved in cytosolic copper transport. In higher plants, CCH has to be transported to specialised cells throu...

    Authors: Helena Mira, Marçal Vilar, Vicent Esteve, Marc Martinell, Marcelo J Kogan, Ernest Giralt, David Salom, Ismael Mingarro, Lola Peñarrubia and Enrique Pérez-Payá

    Citation: BMC Structural Biology 2004 4:7

    Content type: Research article

    Published on:

  2. Intracellular membrane fusion processes are mediated by the spatial and temporal control of SNARE complex assembly that results in the formation of a four-helical bundle, composed of one vesicle SNARE and thre...

    Authors: Andreas Bracher and Winfried Weissenhorn

    Citation: BMC Structural Biology 2004 4:6

    Content type: Research article

    Published on:

  3. The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structur...

    Authors: Alexey Teplyakov, Sadhana Pullalarevu, Galina Obmolova, Victoria Doseeva, Andrey Galkin, Osnat Herzberg, Miroslawa Dauter, Zbigniew Dauter and Gary L Gilliland

    Citation: BMC Structural Biology 2004 4:5

    Content type: Research article

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  4. High-throughput protein structure analysis of individual protein domains requires analysis of large numbers of expression clones to identify suitable constructs for structure determination. For this purpose, m...

    Authors: Christoph Scheich, Dietmar Leitner, Volker Sievert, Martina Leidert, Brigitte Schlegel, Bernd Simon, Ivica Letunic, Konrad Büssow and Anne Diehl

    Citation: BMC Structural Biology 2004 4:4

    Content type: Methodology article

    Published on:

  5. Many characterised proteins contain metal ions, small organic molecules or modified residues. In contrast, the huge amount of data generated by genome projects consists exclusively of sequences with almost no ...

    Authors: Kirill Degtyarenko and Sergio Contrino

    Citation: BMC Structural Biology 2004 4:3

    Content type: Research article

    Published on:

  6. In this paper, we describe cDNA cloning of a new anionic trypsin and a collagenolytic serine protease from king crab Paralithodes camtschaticus and the elucidation of their primary structures. Constructing the ph...

    Authors: Galina N Rudenskaya, Yuri A Kislitsin and Denis V Rebrikov

    Citation: BMC Structural Biology 2004 4:2

    Content type: Research article

    Published on:

  7. The mouse Fv1 (friend virus) susceptibility gene inhibits the development of the murine leukaemia virus (MLV) by interacting with its capsid (CA) protein. As no structures are available for these proteins we h...

    Authors: William R Taylor and Jonathan P Stoye

    Citation: BMC Structural Biology 2004 4:1

    Content type: Research article

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  8. Images of frozen hydrated [vitrified] virus particles were taken close-to-focus in an electron microscope containing structural signals at high spatial frequencies. These images had very low contrast due to th...

    Authors: Ali Samir Saad

    Citation: BMC Structural Biology 2003 3:9

    Content type: Methodology article

    Published on:

  9. Tripeptidyl-peptidase I, also known as CLN2, is a member of the family of sedolisins (serine-carboxyl peptidases). In humans, defects in expression of this enzyme lead to a fatal neurodegenerative disease, cla...

    Authors: Alexander Wlodawer, Stewart R Durell, Mi Li, Hiroshi Oyama, Kohei Oda and Ben M Dunn

    Citation: BMC Structural Biology 2003 3:8

    Content type: Research article

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  10. The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function.

    Authors: Jane E Ladner, Galina Obmolova, Alexey Teplyakov, Andrew J Howard, Pavel P Khil, R Daniel Camerini-Otero and Gary L Gilliland

    Citation: BMC Structural Biology 2003 3:7

    Content type: Research article

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  11. Human serum albumin (HSA) is an abundant plasma protein that binds a wide variety of hydrophobic ligands including fatty acids, bilirubin, thyroxine and hemin. Although HSA-heme complexes do not bind oxygen re...

    Authors: Patricia A Zunszain, Jamie Ghuman, Teruyuki Komatsu, Eishun Tsuchida and Stephen Curry

    Citation: BMC Structural Biology 2003 3:6

    Content type: Research article

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  12. Charging of transfer-RNA with cognate amino acid is accomplished by the aminoacyl-tRNA synthetases, and proceeds through an aminoacyl adenylate intermediate. The lysyl-tRNA synthetase has evolved an active sit...

    Authors: Samantha J Hughes, Julian A Tanner, Alison D Hindley, Andrew D Miller and Ian R Gould

    Citation: BMC Structural Biology 2003 3:5

    Content type: Research article

    Published on:

  13. Protein Kinase Casein Kinase 2 (PKCK2) is an ubiquitous Ser/Thr kinase expressed in all eukaryotes. It phosphorylates a number of proteins involved in various cellular processes. PKCK2 holoenzyme is catalytica...

    Authors: Nambudiry Rekha and N Srinivasan

    Citation: BMC Structural Biology 2003 3:4

    Content type: Research article

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  14. The eukaryotic RNA-dependent RNA polymerase (RDRP) is involved in the amplification of regulatory microRNAs during post-transcriptional gene silencing. This enzyme is highly conserved in most eukaryotes but is...

    Authors: Lakshminarayan M Iyer, Eugene V Koonin and L Aravind

    Citation: BMC Structural Biology 2003 3:1

    Content type: Research article

    Published on:

  15. An efficient building block for protein structure prediction can be tripeptides. 8000 different tripeptides from a dataset of 1220 high resolution (≤ 2.0°A) structures from the Protein Data Bank (PDB) have bee...

    Authors: Sharmila Anishetty, Gautam Pennathur and Ramesh Anishetty

    Citation: BMC Structural Biology 2002 2:9

    Content type: Research article

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  16. Transgenic proteins expressed by genetically modified food crops are evaluated for their potential allergenic properties prior to marketing, among others by identification of short identical amino acid sequenc...

    Authors: Gijs A Kleter and Ad ACM Peijnenburg

    Citation: BMC Structural Biology 2002 2:8

    Content type: Methodology article

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  17. We have previously isolated a stable alternative DNA structure, which was formed in vitro by reassociation of the strands of DNA fragments containing a 62 bp tract of the CA-microsatellite poly(CA)·poly(TG). I...

    Authors: Claire Gaillard, Luda S Shlyakhtenko, Yuri L Lyubchenko and François Strauss

    Citation: BMC Structural Biology 2002 2:7

    Content type: Research article

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  18. Leukocyte Immunoglobulin-like Receptor-1 (LIR-1) and LIR-2 (also known as ILT2 and ILT4 respectively) are highly related cell surface receptors that bind a broad range of class I MHC molecules with low (μM) af...

    Authors: Benjamin E Willcox, Leonard M Thomas, Tara L Chapman, Astrid P Heikema, Anthony P West Jr and Pamela J Bjorkman

    Citation: BMC Structural Biology 2002 2:6

    Content type: Research article

    Published on:

  19. TEL is a transcriptional repressor containing a SAM domain that forms a helical polymer. In a number of hematologic malignancies, chromosomal translocations lead to aberrant fusions of TEL-SAM to a variety of ...

    Authors: Hoang H Tran, Chongwoo A Kim, Salem Faham, Marie-Claire Siddall and James U Bowie

    Citation: BMC Structural Biology 2002 2:5

    Content type: Research article

    Published on:

  20. Quantitative information on the types of inter-atomic interactions at the MHC-peptide interface will provide insights to backbone/sidechain atom preference during binding. Qualitative descriptions of such inte...

    Authors: Png Eak Hock Adrian, Ganapathy Rajaseger, Venkatarajan Subramanian Mathura, Meena Kishore Sakharkar and Pandjassarame Kangueane

    Citation: BMC Structural Biology 2002 2:2

    Content type: Research article

    Published on:

  21. The function of proteins is a direct consequence of their three-dimensional structure. The structural classification of proteins describes the ways of folding patterns all proteins could adopt. Although, the p...

    Authors: Vishal Agrawal and Radha KV Kishan

    Citation: BMC Structural Biology 2001 1:5

    Content type: Research article

    Published on:

  22. This work represents an extensive MD simulation / water-dynamics studies on a series of complexes of inhibitors (leupeptin, E-64, E-64-C, ZPACK) and plant cysteine proteases (actinidin, caricain, chymopapain, ...

    Authors: Suparna Bhattacharya, Sreya Ghosh, Sibani Chakraborty, Asim K Bera, Bishnu P Mukhopadhayay, Indrani Dey and Asok Banerjee

    Citation: BMC Structural Biology 2001 1:4

    Content type: Research article

    Published on:

  23. Several Retinoic Acid Receptors (RAR) agonists have therapeutic activity against a variety of cancer types; however, unacceptable toxicity profiles have hindered the development of drugs. RAR agonists presenti...

    Authors: Matthieu Schapira, Bruce M Raaka, Herbert H Samuels and Ruben Abagyan

    Citation: BMC Structural Biology 2001 1:1

    Content type: Research article

    Published on:

2017 Journal Metrics

  • Citation Impact
    1.308 - 2-year Impact Factor
    1.609 - 5-year Impact Factor
    0.643 - Source Normalized Impact per Paper (SNIP)
    1.024 - SCImago Journal Rank (SJR)

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    Social Media Impact
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