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Section edited by Jean-Luc Pellequer

This section incorporates all aspects of the structural analysis of biological macromolecules using techniques in microscopy including but not limited to: studies incorporating substantial analysis by electron microscopy, atomic force microscopy, tomography and/or chromatography as well as image processing tools.

  1. P-glycoprotein (ABCB1) is an ATP-binding cassette transporter that plays an important role in the clearance of drugs and xenobiotics and is associated with multi-drug resistance in cancer. Although several P-g...

    Authors: Nopnithi Thonghin, Richard F. Collins, Alessandro Barbieri, Talha Shafi, Alistair Siebert and Robert C. Ford
    Citation: BMC Structural Biology 2018 18:17
  2. Synchrotron radiation facilities are pillars of modern structural biology. Small-Angle X-ray scattering performed at synchrotron sources is often used to characterize the shape of biological macromolecules. A ...

    Authors: Luca Costa, Alexander Andriatis, Martha Brennich, Jean-Marie Teulon, Shu-wen W. Chen, Jean-Luc Pellequer and Adam Round
    Citation: BMC Structural Biology 2016 16:18
  3. Picking images of particles in cryo-electron micrographs is an important step in solving the 3D structures of large macromolecular assemblies. However, in order to achieve sub-nanometre resolution it is often ...

    Authors: Thai V Hoang, Xavier Cavin, Patrick Schultz and David W Ritchie
    Citation: BMC Structural Biology 2013 13:25